heme positivebar stooll什么意思

来源：蜘蛛抓取(WebSpider) 时间：2015-02-28 01:33 标签： solidworkstoolbox
Pneumatosis
Intestinalis_百度文库
两大类热门资源免费畅读
续费一年阅读会员，立省24元！
文档贡献者
评价文档：
Pneumatosis
Intestinalis
把文档贴到Blog、BBS或个人站等：
普通尺寸(450*500pix)
较大尺寸(630*500pix)
大小：2.61MB
登录百度文库，专享文档复制特权，财富值每天免费拿！
你可能喜欢 上传我的文档
 下载
 收藏
愿得一心人，白首不相离
 下载此文档
正在努力加载中...
pneumatosis
intestinalis
下载积分：1000
内容提示：pneumatosis
intestinalis
文档格式：PDF|
浏览次数：0|
上传日期： 01:03:16|
文档星级：
该用户还上传了这些文档
pneumatosis
intestinalis
官方公共微信Gemcitabine-related radiation recall in a patient with pancreatic cancer.
- PubMed - NCBI
The NCBI web site requires JavaScript to function.
FormatSummarySummary (text)AbstractAbstract (text)MEDLINEXMLPMID ListChoose DestinationFileClipboardCollectionsE-mailOrderMy BibliographyCitation managerFormatSummary (text)Abstract (text)MEDLINEXMLPMID ListCSVCreate File1 selected item: FormatSummarySummary (text)AbstractAbstract (text)MEDLINEXMLPMID ListMeSH and Other DataE-mailSubjectAdditional textE-mailAdd to ClipboardAdd to CollectionsOrder articlesAdd to My BibliographyGenerate a file for use with external citation management software.Create File
):107-11.Gemcitabine-related radiation recall in a patient with pancreatic cancer.1, , .1Yale University School of Medicine, New Haven, Connecticut 06520, USA. wasif.saif@yale.eduAbstractRadiation recall refers to inflammatory reactions triggered by chemotherapeutic agents and develops cutaneously in the previously irradiated areas. Such agents include anthracyclines, taxanes and capecitabine. Radiation recall related to gemcitabine has been reported in lung and breast cancer. Similar phenomenon associated with gemcitabine, the only FDA-approved drug for pancreatic cancer, is rarely reported. We report a patient with inoperable pancreatic cancer who developed gastrointestinal bleeding secondary to radiation-recall related to gemcitabine and review literature. A 57-year-old white male with unresectable pancreatic cancer received capecitabine in combination with radiation therapy followed by capecitabine alone given over approximately a 3-month time period. Computed tomography re-evaluation demonstrated a new liver lesion. The patient was then treated with gemcitabine and irinotecan. On day 15 of cycle 1, he reported progressive worsening of weakness and fatigue, and melena. Physical examination revealed hypotension (84/47 mmHg) and heme-positive stool on rectal examination. He denied aspirin or non-steroidal anti-inflammatory drug use. Chemotherapy was held. Hematocrit was 20% (previously 33%). He was transfused with 3 units of packed red blood cells. An esophago-gastro-duodenal examination was performed which showed antritis and duodenitis consistent with radiation therapy. A single site of oozing was injected with epinephrine. The diffuse gastritis was aggressively treated with proton pump inhibitors. The patient's hematocrit eventually stabilized and was 30% at discharge. Gemcitabine was not resumed. Radiation recall from gemcitabine is rare, but can potentially arise in any site that has been previously irradiated. Gemcitabine should be added to the list of drugs known to cause radiation recall. Treating physicians must be aware of this potential toxicity from gemcitabine either given concomitantly or followed by radiation. We suggest discontinuing gemcitabine if radiation recall is observed. Further studies are warranted into the pathogenesis of this unique phenomenon.PMID:
[PubMed - indexed for MEDLINE]
Publication TypesMeSH TermsSubstancesFull Text SourcesOther Literature SourcesMedical
Supplemental Content
External link. Please review our .

我要回帖

更多关于 solidworkstoolbox 的文章

 

随机推荐