欢迎访问《生态毒理学报》编辑部网站!
&|&&|&&|&&|&&|&&|&&|&&|&&|&
张效伟教授简介
&&& & 张效伟教授早年是南京大学的一名优秀本科毕业生，曾先后前往香港，澳大利亚，美国和加拿大的著名环境生态毒理学实验室攻读硕士和博士学位，以及开展学术交流与合作研究工作。 博士研究师从世界著名环境科学家，美国国家环境保护局科学顾问，加拿大环境毒理学首席科学家，John P. Giesy教授。在北美学习和工作期间，他出色地完成了多项由美国环保局STAR计划资助的环境生态毒理学研究项目。这些工作包括基因组学和基于细胞的生物筛选技术在环境化学品的毒性测试和风险评估领域的研究和应用。研究的成果不仅发表在高质量的学术杂志期刊上， 而且也成为美国制定国家环境政策的重要依据。 其中，由他作为主要研发人员完成的Steroidogenesis Assay 在2009年初被美国环保局采纳为官方环境内分泌干扰物质筛选的标准方法。目前该方法已经通过世界经济合作与发展组织（OECD）的认可，成为全球通用的化学品安全性测试国际标准。
张效伟教授积极参加各类重要国际学术交流活动。曾多次在北美，欧洲和亚洲重要的环境生态毒理学学术会议上报告。在2006年加拿大蒙特利尔市举行的环境毒理学和化学学会（SETAC）年会上，他的学术报告被评为最优秀的报告之一。
至今，张效伟教授已发表SCI论文22篇，他引用超过130 次，他也是一项美国专利的第一发明人。
教育背景：
，南京大学环境学院，本科，指导老师：金洪钧教授 和于红霞教授
，香港城市大学，硕士，指导老师：Prof. Rudolf Wu和 Prof. Paul Lam
，美国密歇根州立大学，应用统计学硕士；动物学和环境毒理学博士，指导老师：Prof. John P. Giesy
&工作经历：
2009.12 - 至今，南京大学环境学院， 教授
2009.01 - 2009.12，加拿大萨斯喀气温大学， 高级研究助理
2008.01 - 2008.12，加拿大萨斯喀气温大学， 博士后
2003.01 - 2004.12，美国密歇根州立大学食品安全与毒理学国家研究中心， 访问学者
2000.01 - 2000.12，香港城市大学海岸污染研究中心，访问科学家
&研究方向：
1. 环境污染物的致毒分子机制和新型生物监测方法研究
2. 环境化学品的生物毒性筛选和安全性评估方法研究
3. 生态环境健康风险评估理论和方法研究
学术成就：
[1] Zhang Xiao-wei, Newsted John L., Hecker Markus, Higley EB, Jones Paul D., Giesy John P.Classification of chemicals based on concentration-dependent toxicological data using ToxClust.Environmental Science & Technology,):.
[2] Wan Yi, Wiseman Steve, Chang Hong, Zhang Xiao-wei, Jones Paul D., Hecker Maekus, Kannan Kurunthachalam, Tanabe Shinsuke, Hu Jian-ying, Lam Michael H. W., Giesy John P.Origin of hydroxylated brominated diphenyl ethers: natural compounds or man-made flame retardants?Environmental Science and Technology,):.
[3] Zhang Xiao-wei, Yu Richard M. K., Jones Paul D., Lam Gabriel K. W., Newsted John L., Gracia Tannia, Hecker Markus, Hilscherova Klara, Sanderson J. Thomas, Wu Rudolf S. S., Giesy John P.Quantitative RT-PCR methods for evaluating toxicant-induced effects on steroidogenesis using the H295R cell line. Environmental Science & Technology,):.
[4] Ji Kyunghee, Choi Kyungho, Lee Sangwoo, Park Saerom, Khim Jong Seong, Jo Eun-Hye, Choi Kyunghee, Zhang Xiao-wei, Giesy John P.Effects of sulfathiazole, oxytetracycline and chlortetracycline on steroidogenesis in the human adrenocarcinoma (H295R) cell line and freshwater fish Oryzias latipes. Journal of Hazardous Materials,-3):494-502.
[5] Liu Chun-sheng, Zhang Xiao-wei, Chang Hong, Jones Paul, Wiseman Steve, Naile Jonathan, Hecker Markus, Giesy John P., Zhou Bing-sheng.Effects of Fluorotelomer Alcohol 8:2 FTOH on Steroidogenesis in H295R Cells: Targeting the cAMP Signalling Cascade.Toxicology and Applied Pharmacology,): 222-228.
[6] He Yu-he, Wiseman Steve B., Zhang Xiao-wei, Hecker Markus, Jones Paul D., El-Din Mohamed Gamal, Martin Jonathan W., Giesy John P.Ozonation attenuates the steroidogenic disruptive effects of sediment free oil sands process water in the H295R cell line.Chemosphere,):578-584.
[7] Higley Eric B., Newsted John L., Zhang Xiao-wei, Giesy John P., Hecker Markus.Assessment of chemical effects on aromatase activity using the H295R cell line.Environmental Science and Pollution Research,):.
[8] Han Sunyoung, Choi Kyungho, Kim Jungkon, Ji Kyunghee, Kim Sunmi, Ahn Byeongwoo, Yun Junheon, Choi Kyunghee, Khim Jong Seong, Zhang Xiao-wei, Giesy John P.Endocrine disruption and consequences of chronic exposure to ibuprofen in Japanese medaka (Oryzias latipes) and freshwater cladocerans Daphnia magna and Moina macrocopa.Aquatic Toxicology,):256-264.
[9] Chang Hong, Wan Yi, Naile Jonathan, Zhang Xiao-wei, Wiseman Steve, Hecker Markus, Lam Michael H. W., Giesy John P., Jones Paul D. Simultaneous quantification of multiple classes of phenolic compounds in blood plasma by liquid chromatography-electrospray tandem mass spectrometry.Journal of Chromatogrphy A,(4):506-513.
[10] Park Jun-Woo, Tompsett Amber R., Zhang Xiao-wei, Newsted John L., Jones Paul D., Au Doris W., Kong Richard, Wu Rudolf S. S., Giesy John P., Hecker Markus.Advanced fluorescence in situ hybridization to localize and quantify gene expression in Japanese medaka (Oryzias latipes) exposed to endocrine-disrupting compounds.Environmental Toxicology and Chemistry,):.
[11] Zhang Xiao-wei, Moore Jeremy N., Newsted John L., Hecker Markus, Zwiernik Matthew J., Jones Paul D., Bursian Steven J., Giesy John P.Sequencing and characterization of mixed function monooxygenase genes CYP1A1 and CYP1A2 of Mink (Mustela vison) to facilitate study of dioxin-like compounds.Toxicology and Applied Pharmacology,):306-313.
[12] Moore Jeremy N., Newsted John L., Hecker Markus, Zwiernik Matthew J., Fitzgerald Scott D., Kay Denise P., Zhang Xiao-wei, Higley Eric B., Aylward Lesa L., Beckett Kerrie J., Budinsky Robert A., Bursian Steven J., Giesy John P.Hepatic P450 enzyme activity, tissue morphology and histology of mink (Mustela vison) exposed to polychlorinated dibenzofurans.Archives of Environmental Contamination and Toxicology,):416-425.
[13] Zhang Xiao-wei, Hecker Markus, Park June-Woo, Tompsett Amber R., Jones Paul D., Newsted John, Au Doris W. T., Kong Richard, Wu Rudolf S. S., Giesy John P.Time-dependent transcriptional profiles of genes of the hypothalamic-pituitary-gonadal axis in medaka (Oryzias latipes) exposed to fadrozole and 17beta- trenbolone.Environmental Toxicology and Chemistry,): .
[14] Park June-Woo, Tompsett Amber, Zhang Xiao-wei, Newsted John L., Jones Paul D., Au Doris, Kong Richard, Wu Rudolf S. S., Giesy John P., Hecker Markus.Fluorescence in situ hybridization techniques (FISH) to detect changes in CYP19a gene expression of Japanese medaka (Oryzias latipes).Toxicology Applied Pharmacology,):226-235.
[15] Zhang Xiao-wei, Hecker Markus, Park June-Woo, Tompsett Amber R., Newsted John, Nakayama Kei, Jones Paul D., Au Doris, Kong Richard, Wu Rudolf S. S., Giesy John P.Real-time PCR array to study effects of chemicals on the Hypothalamic-Pituitary-Gonadal axis of the Japanese medaka. Aquatic Toxicology,):173-182.
[16] Zhang Xiao-wei, Hecker Markus, Jones Paul D., Newsted John, Au Doris, Kong Richard, Wu Rudolf S. S., Giesy John P.Responses of the medaka HPG axis PCR array and reproduction to prochloraz and ketoconazole. Environmental Science & Technology,):.
[17] Gracia Tannia, Jones Paul D., Higley Eric B., Hilscherova Klara, Newsted John L., Murphy Margaret B., Chan Alice K. Y., Zhang Xiao-wei, Hecker Markus, Lam Paul K. S., Wu Rudolf S. S., Giesy John P.Modulation of steroidogenesis by coastal waters and sewage effluents of Hong Kong, China, using the H295R assay. Environmental Science and Pollution Research,):332-343.
[18] Gracia Tannia, Hilscherova Klara, Jones Paul D., Newsted John L., Higley Eric B., Zhang Xiao-wei, Hecker Markus, Murphy Margaret B., Yu Richard M. K., Lam Paul K. S., Wu Rudolf S. S., Giesy John P.Modulation of steroidogenic gene expression and hormone production of H295R cells by pharmaceuticals and other environmentally active compounds.Toxicology Applied Pharmacology,):142-153.
[19] Gracia Tannia, Hilscherova Klara, Jones Paul D., Newsted John L., Zhang Xiao-wei, Hecker Markus, Higley Eric B., Sanderson J. T., Yu Richard M. K., Wu Rudolf S. S., Giesy John P. The H295R system for evaluation of endocrine-disrupting effects. Ecotoxicology and Environmental Safety,):293-305.
[20] Xu yan, Yu Richard M. K., Zhang Xiao-wei, Murphy Margaret B., Giesy John P., Lam Michael H. W., Lam Paul K. S., Wu Rudolf S. S., Yu Hong-xia. Effects of PCBs and MeSO2-PCBs on adrenocortical steroidogenesis in H295R human adrenocortical carcinoma cells.Chemosphere,):772-784.
[21] Sun Shi-lei, Cheng Shu-pei, Wan Yu-qiu, Zhang Xu-xiang, Shi Lei, Zhu Cheng-jun, Yu Hong-xia, Luo Xiang, Lu Jian-hua, Zhang Xiao-chun, Wang Gui-lin, Wang Hong-li, Yu Jing-zhou, Chen Jun. Pilot regulation of MnP-SA for treating PTA wastewater.Journal of Environmental Sciences-China,):375-378.
[22] Zhang Xiao-wei, Wu Rudolf S. S., Fu Wen-yu, Xu Li-hong, Lam Paul K. S.Production of reactive oxygen species and 8-hydroxy-2&deoxyguanosine in KB cells co-exposed to benzo[a]pyrene and UV-A radiation.Chemosphere,):.
[23] Hilscherova Klara, Jones Paul D., Gracia Tannia, Newsted John L., Zhang Xiao-wei, Sanderson J. T., Yu Richard M. K., Wu Rudolf S. S., Giesy John P.Assessment of the effects of chemicals on the expression of ten steroidogenic genes in the H295R cell line using real-time PCR.Toxicological Sciences,):78-89.
Zhang X.*, Hecker, M. and Giesy, J.P. Steroidogenesis modified H295R Cells for Screening of Endocrine Disrupting Chemicals (US Provisonal 61/242,822)
重要国际学术会议摘要
Society of Environmental Toxicology and Chemistry (SETAC) - North America
（北美环境毒理学和化学学会）
&The effects of TCDD, PeCDF and TCDF on development of maxillary and mandibular squamous epithelial proliferation in mink& With J. Moore, et al. To: 30th Annual Meeting. 19-23 November 2009.
New Orleans, LA, USA.
&The effects of TCDD, PeCDF and TCDD on reproduction of mink and growth and survivability of their offspring& With J. Moore, et al. To: 30th Annual Meeting. 19-23 November 2009.
New Orleans, LA, USA.
&Origin of Hydroxylated Brominated Diphenyl Ethers: Natural Compounds or Man-made Flame Retardants? & With Wan, Y., et al. To: 30th Annual Meeting. 19-23 November 2009.
New Orleans, LA, USA.
&Canidae Exposure to Polychlorinated Dibenzofurans (PCDFs) of the Tittabawassee River Floodplain, Midland, MI& With J. Moore, et al. To: 30th Annual Meeting. 19-23 November 2009.
New Orleans, LA, USA.
&Effects of Ozone-Treated and Untreated Sediment-Free Oil Sand Processed Water on In Vitro Steroidogenesis & With Y. He, et al. To: 30th Annual Meeting. 19-23 November 2009.
New Orleans, LA, USA.
&Testing and Risk Assessment of Chemicals that Impact Highly Adaptive Biological Systems: The Case of Endocrine Systems& With J. Nichols, et al. To: 30th Annual Meeting. 19-23 November 2009.
New Orleans, LA, USA.
&Application of a medaka HPG axis real time PCR array method to environmental chemical screening.&
To: 29th Annual Meeting. 16-20 November 2008.
Tampa, FL, USA.
&Characterization of mixed function monooxygenase genes CYP1A1 and CYP1A2 of Mink (Mustela vison) to facilitate study on dioxin-like compounds& To: 29th Annual Meeting. 16-20 November 2008.
Tempa, FL, USA.
&White sturgeon growth, morphology, and survival after exposure to Columbia River surface water at two sites in British Columbia, Canada.& With A.R. Tompsett, D. Vardy, M. Hecker, S. Wiseman, K. Liber, J.P. Giesy. To: 29th Annual Meeting. 16-20 November 2008.
Tampa, FL, USA.
&Testing of five model endocrine disrupting chemicals using medaka hypothalamic- pituitary-gonadal (BHG) axis model and RT-PCR array method&.
To: 28th Annual Meeting, November 11-15, 2007, Milwaukee, WS, USA.
&Gene Expression and Histological Structure as Biomarkers of Chemical Exposure in Japanese Medaka.& With AR. Tompsett, J. Park, M. Hecker, P.D. Jones, J.L. Newsted, D. Au and J. Giesy. To: 28th Annual Meeting, November 11-15, 2007, Milwaukee, WS. USA. Invited
&Development and Validation of a Quantitative Real Time RT-PCR System to Study Chemical Induced Effects on the HPG-axis of Medaka (Oryzias latipes)&. To: 27th Annual Meeting, November 5-9, 2006, Montreal, Canada.
&A mixture model for chemical clustering --- an application using data from H295R cell assays&. To: 27th Annual Meeting, November 5-9, 2006. Montreal, Canada.
&Elucidating Changes in Aromatase (CYP19) Gene Expression in Japanese Medaka (Oryzias latipes) Exposed to Fadrozole: Q RT-PCR and its comparison with ISH methods&. With J. Park, A.Tompsett, M. Hecker, P.D. Jones, J.L and J.Giesy. Newsted. To: 27th Annual Meeting, November 5-9, 2006, Montreal, Quebec, Canada.
&Data Analysis Approaches for Interpreting Complex Toxicogenomic Data Sets.& With P.D. Jones, J.L. Newsted, T. Gracia, J.T Sanderson, K. Hilscherova and J. Giesy. To: 27th Annual Meeting, November 5-9, 2006, Montreal, Quebec, Canada.
&Multiplex in situ Hybridization to Detect CYP19a and b Gene Expression Patterns Along the HPG-axis of the Japanese Medaka (Oryzias latipes).& With J. Park, A.R. Tompsett,
M. Hecker, P.D Jones, and J.L. Newsted and J Giesy.. To: 27th Annual Meeting, November 5-9, 2006, Montreal, Quebec, Canada.
&A Comparison of H295R, R2C and JEG-3 Cells as Screening Tools for Effects on Steroidogenesis&.
To: 26th Annual Meeting, November 13-17, 2005, Baltimore, MD.
&Quantitative Assessment of Chemical Effects on Steroidigenic Enzymes in H295R Cells Line Using Q-RT-PCR&. With: T. Gracia, K. Hilscherova, P. D. Jones, J. T. Sanderson and J. L. Nested and J. Giesy. To: 25th Annual Meeting, November 14-18, 2004, Portland, Oregon.
&A Cell Culture Based Assay for the Measurement of Xenobiotic Effects on Steroid Production&. With: P. D. Jones, M. Heckeer, T. Gracia, J. T. Sanderson and J. L. Newsted and J. Giesy. To: 25th Annual Meeting, November 14-18, 2004, Portland, Oregon.
SETAC-Europe
（欧洲环境毒理学和化学学会）
&Evaluation of the Endocrine-Disrupting Potential of Bisphenol A Using the H295R Steroidogenesis Assay and Small Fish Model&. To: 19th Annual Meeting, 31 May- 4 June, 2009, G&teborg, Sweden.
&Development of a H295R Cell Line Test to Evaluate Toxicant-Induced Effects on Steroidogenesis&. With M. Hecker, M. Murphy, T. Gracia, P. Jones, T. Sanderson, J. Newsted and J Giesy. To: 15th Annual Meeting, May 22-26, 2005, Lille, France.
&Effects of Chemicals on Steroidogenesis in H295R Cells&. With T. R. Gracia, K. Hilscherova, P. D. Jones, J.T. Sanderson, J.L. Newsted and J. Giesy. To: 14th Annual Meeting, April 18-22, 2004, Prague, Czech Republic.
&Evaluating toxicant-induced effects on steroidogenesis using the H295R cell line&. To: 14th Annual Meeting of the, May 2004. Prague, Czech.
&Effect of benzo[a]pyrene and ultraviolet A on KB cells: relationship between ROS production and 8-Hydroxy-2&-deoxyguanosine (8-OHdG) formation&. To: 12th Annual Meeting, Vienna, Austria. May 2002.
SETAC-Ohio Valley Chapter
（环境毒理学和化学学会---俄亥俄河谷分会）
&Comparison on the toxicity profile of PFOA and PFOS using genomic data&. To: 23rd Annual Meeting. Fort Waney, Indiana, USA. 20-21, Apr 2006.
International Science Forum on Computational Toxicology
（计算毒理学国际科学论坛）
&Human adrenocarcinoma (H295R) cells for the rapid in vitro determination of effects on steroidogenesis: gene expression, sex steroid concentrations, and aromatase activity&. With N., John, M. Hecker and J. Giesy.
21&23, May 2007. Research Triangle Park, North Carolina, USA.
Society of Toxicology
（美国毒理学学会）
&Profiling Gene Expression in Human H295R Adrenocortical Carcinoma Cells and Rat Testes to Identify Pathways of Toxicity for Conazole Fungicides&. With H. Re, J. E. Schmid, J. Retief, Y. Turpaz, X. Zhang, P. D. Jones, J. L. Newsted, J. P. Giesy, D. C. Wolf, C. R. Wood, W. Bao and D. J. Dix. To: 44th Annual Meeting, March 6-10, 2005, New Orleans.
Dioxin Conference
（二恶英大会）
Characterization of mixed function monooxygenase genes CYP1A1 and CYP1A2 in mink (mustela vison) exposed to polychlorinated dibenzofurans (PCDFs) With Jeremy N. Moore, John L. Newsted, Matthew J. Zwiernik, Markus Hecker, Paul D. Jones, Steven J. Bursian, John P. Giesy. 17-22, August 2008, Birmingham, UK.
&Gene expression and histological structure as biomarkers of chemical exposure in Japanese medaka.& With A. Tompsett, J.-W. Park, J.L. Newsted, M. Hecker, P.D. Jones and J. Giesy. 34th Aquatic Toxicity Workshop, Halifax, Nova Scotia, October 2, 2007.
Aquatic Toxicology Workship, Canada
（加拿大水生毒理学会议）
&Evaluation of Environmental Endocrine Disrupting Chemicals Using Japanese Medaka HPG axis model&. To 35th Aquatic Toxicology Workshop, Saskatoon, SK. Oct 5-10, 2008.
&Elucidating Changes in Aromatase (CYP19) Gene Expression in Japanes Medaka (Oryzias latipes) Exposed to Fadrazol: In situ Hybridization in a Whole Animal Model. With A. Tompsett, J.W. Park, M. Hecker, J.L. Newsted, P.D. Jones, D. Au, P.K.S. Lam, R. S.S. Wu and J. Giesy. To: Institute of Oceanography, Chinese Academy of Sciences, and State Key Laboratory of Marine Ecology & Environmental Sciences, Qingdao, PR China, January 9, 2007. Invited
&Development of a H295R Cell Screening Test to Evaluate Toxicant-Induced and Hypoxic Effects on Steroidogenesis&. . With M. Hecker, M. Murphy, T. Gracia, P.D. Jones, X. Zhang, J.L. Newsted, R. Yu, R.S.S. Wu and J.Giesy. To: Symposium, Centre for Marine Pollution and Environmental Research and Innovative Technology, City University of Hong Kong, Kowloon, Hong Kong, China, November 30-December 1, 2005.
&Mechanistic classification of environmental endocrine disrupting chemicals&. The 5th international conference on marine pollution and ecotoxicology. Hong Kong, P. R. China, 3-6, Jun, 2007
&Evaluation of Environmental Endocrine Disrupting Chemicals Using the Medaka HPG Axis Model& The The 5th International Symposium on Persistent Toxic Substances. Beijing, P.R. China, September 21-24, 2008
&Toxicity pathway-based approaches to evaluate the impact of environmental chemicals.& International Conference on Water Pollution & Management. Suzhou, China May 23 & 27, 2009 (Invited Plenary Keynote)
&Endocrine Disruptor Mechanisms and Screening: Beyond Receptor Binding&.
With J. Giesy, M. Hecker, and D. Au.
To: International Conference on Water Pollution and Management, May 23-27, Suzhou, China.
Invited Plenary Keynote　　　　
学术兼职（SCI Journal Reviewer
Analytical & Bioanalytical Chemistry
Marine Pollution Bulletin
Cell Biology International
Chemosphere
Comparative Biochemistry and Physiology
Ecotoxicology and Environmental Safety
Environmental Science and Pollution Research
General and Comparative Endocrinology
Science of the Total Environment
Toxicology and Applied Pharmacology
Toxicological & Environmental Chemistry
您是第1163786位访问者 &&京ICP备
主办单位：中国科学院生态环境研究中心&&&&
单位地址：北京市海淀区双清路18号
&服务热线：010-&&&&&&
传真：010-&&&&&& 邮编：100085
&& Email：上海交通大学医学院研究生导师简介 陆颖理
第九人民医院
三级学科/ 专业领域:
内分泌与代谢病
博士生导师
专业学位导师:
联系方式: .cn 上海市制造局路639号，上海大学院附属第九人民医院内分泌代谢科，200011 研究方向 (点击浏览详细信息)糖尿病的基础和临床研究社会任职博士，大学教授, 博士生导师，主任医师，上海大学院附属第九人民医院内分泌科学科带头人，九院内分泌代谢科主任，临床院副院长,内科教研室主任。上海市内科学会副主任委员，中华糖尿病学会委员，上海糖尿病康复协会常委，上海市大内科住院医师培训基地评审委员兼秘书，上海内分泌疑难病例学组成员。上海市医疗事故鉴定专家，上海市中西医结合学会委员，中华糖尿病杂志编委，上海大学院版杂志审稿人，International Journal of Clinical Medicine杂志审稿人科研项目项目编号项目名称课题来源起止时间科研经费承担职责胃肠重塑与糖代谢稳态新调控机制的示踪研究国家自然科学基金16-1270万元课题负责人 脂肪肝和高脂血症的早期干预及其原理验证研究科技部 97316-1260万元子课题负责人0早期对血糖调控相关脏器的诊断及治疗预防糖尿病的研究上海市科委12-1210万元课题负责人大鼠PCOS糖代谢稳态失衡的模型建立与同位素示踪研究上海市科委重点基金13-1215万元课题负责人糖尿病前期机体葡萄糖代谢紊乱发病机理的研究国家自然基金13-1231万元课题负责人10JC1409002用示踪剂技术探讨高脂诱导肥 胖糖脂代谢稳态失衡的调控制上海市科委重点基金12-1215万元课题负责人学术论文 (#为通讯作者,*为共同第一作者)1、Hua-Ling Zhai, Hui Wu, Hui Xu, Pan Weng, Fang-Zhen Xia, Yi Chen and Ying-Li Lu. Trace glucose and lipid metabolism in highandrogen and high-fat diet induced polycysticovary syndrome rats. Reproductive Biology and Endocrinology,2012;2、Lu YL, Zhou DQ, Zhai HL, Wu H, Guo ZK.. Decreased hepatic glucose production in obese rats by dipeptidyl peptidase-IV inhibitor sitagliptin. CMJ,):1690-43、Hui Wua, Fang-zhen Xiaa, Hui Xua, Hua-ling Zhaia, Mei-fang Zhangb, Hui-xin Zhanga, Yan-xiang Lia,Ying Lia, Ting Gua, Li-min Maa, Ying-li Lu#. Acute effects of different glycemic index diets on serum motilin, orexinand neuropeptide Y concentrations in healthy individuals. Neuropeptides,-1184、Yan-xiang Li, Bo-ren Jiang, Ying Li, Fang-zhen Xia, Jiao Yu, Li-zhen Yang, Shi-chao, Yingli Lu（陆颖理）.
Mitochondrial apoptotic pathways: a mechanism for low androgen-induced vascular endothelial injury in male rats.. Hormone and Metabolic Research, J43(6):374-3795、CHEN Yi, Xin WANG,Mei-fang ZHANG,Yan-xiang LI, Ying LI,Ting GU, Fang-zhen XIA, Jiao YU, Ying-li LU（陆颖理）#. The short reaction of C-peptide, GLP-1, Ghrelin and Endomorphin-1 for Different Style Diet in Type 2 Diabetic Patients. . Chinese Medical Journal,4(21):6、.Lu Y（陆颖理）#, Jiang B, Xia F, . Changes of pituitary and penile structure in male adult rats following castration and high-fat diet.. J Endocrinol Invest,1 F34(2):111-67、Ying Li, Lijuan Zhao, Fangzhen Xia, Yanxiang Li, Yingli Lu（陆颖理）. Function of hepatic oval cells under high glucose. Frontier in bioscience,4(4):627-338、 Xia FZ, Lu YL（陆颖理）#, Chen Y, Gu T, Zhang HX, Yu J, Zhao LJ .. Peripheral endomorphin-1 levels are suppressed in diabetic patients. Diabetes Res Clin Pract,;(17):9、YL Lu#, TT Ye, Y Chen, J Yu,LJ Zhao, NJ Wang, BR Jiang, J Qiao and LZ Yang. Rosiglitazone Protects diabetic rats from liver destruction. J.Endocrinol.Invest,-78010、)LU Ying-li（陆颖理）#, YE Ting-ting, XIA Fang-zhen, WANG Ning-jian , YANG Hua, CHEN Yi. Isolation of Hepatic Oval Cells from Different Model Rats Including Diabetic Rats.
Journal of Shanghai Second Medical University,）：7-1111、陆颖理#,叶婷婷,杨华,陈奕,余娇,赵丽娟,夏芳珍,王宁荐,施超,乔洁,叶林,林东平,吴万龄. 高糖下大鼠主动脉内皮细胞COX-2mRNA表达的变化. 中华内分泌代谢杂志,):382-38312、朱惠#,陆颖理,张惠新, 夏芳珍,顾婷,陈奕,叶婷婷,杨华. 老年2型糖尿病患者胰高血糖素对血糖、血压变化的反应. 中华内分泌代谢杂志,):295-29613、Lu YL（陆颖理）#,Jimbu YM, Chen Y, Zhao JB, Ye TT, Yang H.
The Effects of Rosiglitazione on Renal Artery Endothelium in Diabetic Rats. Exp Clin Endocrinol Diabetes,7C540. （SCI）14、Lu YL（陆颖理）#, Kuang L, Zhu H, Wu H, Wang XF, Pang YP, Wang NJ, Yu DL.
Changes in aortic endothelium ultrastructure in male rats following castration, replacement with testosterone and administration of 5α-reductase inhibitor. Asian J Androl,):843-847.（SCI）15、 陆颖理#,吴晖,朱惠,施超,朱岚,庞玉萍,杨裕国,吴万龄. 罗格列酮对糖尿病大鼠心肌超微结构、心钠素mRNA表达的影响. 中华内分泌代谢杂志,16、 陆颖理#,张丽,朱岚,赵江波, 吴晖,王宁荐, 王雪芳,俞丹璐. 糖尿病大鼠心肌超微结构改变及PPARgamma配体对其作用的研究. Journal of zhejiang university(Medical Sciences),:.245-250 (IM收录)17、邵一川#,陆颖理,缑东元. 全身炎症反应综合征患者的甲状腺激素水平变化。. 中华内分泌代谢杂志,):61-6218、LU Ying-li （陆颖理）#,Wang Ning-jian , Zhu Lan , WANG Guo-xing , WU Hui , KUANG Lin , ZHU Wen-ming. Investigation of iodine concentration in salt, water and soil along the coast of Zhejiang, China.
J Zhejiang Univ SCIENCE B,):.(IM)19、Lu YL（陆颖理）#, Hu SJ,Shen ZJ, Shao YC. Changes of macrovascular endothelial ultrastructure and gene expression of endothelial nitric oxide synthase in diabetic rats. CMJ,5-1169.（SCI）20、Lu YL（陆颖理）*,Shen ZJ, Wang H, Chen SW, Zhou XL, Chen ZD. Ultrastructural changes of penile tunica albuginea in diabetic rats. Asian Journal of Andrology.,-368.(SCI)版权所有 ? 2009 上海大学研究生院院分院上海市重庆南路227号 邮编：200025 邮件：yjsy@ 总机：
&&&&&&&&&&
&&&&&&&&&&
&&&&&&&&&&